The life expectancy of any individuals depends on the type of EDS. The average life expectancy can be as low as 48 years old in those with vascular EDS, due to the risk of developing an aneurysm or other complication of major blood vessels. More than 25% of those diagnosed with vascular EDS have experienced a medical complication of the condition by the age of 20. More than 80% have experienced a complication by the age of 40. In other types of EDS the average life expectancy is higher, however, they are still at risk of complications for their condition, impacting quality of life, such as joint dislocation and chronic pain.