Cannabinoid Receptor

Yes. Cannabinoid receptors are part of the endocannabinoid system and they are found on the surface of cells throughout the body. They interact with endocannabinoids made by the body and can also respond to cannabinoids in prescribed medical cannabis.

Cannabinoid receptors are a component of the ECS. Their activation is involved in regulating various functions, including mood, appetite, sleep, memory, and the immune system. While research is still developing, many scientists believe that these receptors contribute to maintaining balance in the body, also called homeostasis.

Cannabinoid receptors are widely distributed. The two main types are:

•  CB1 receptors – mainly located in the brain spinal cord and peripheral nerves.
• CB2 receptors – more common in the immune system and peripheral tissues.
  Because they are found throughout the body, cannabinoid receptors can influence a range of biological processes.

There is no evidence that cannabinoid receptors may become damaged. People with certain conditions may have lower or higher levels of cannabinoid receptors available on the surface of their cells. This is an emerging area of research interest to examine the role of the endocannabinoid system in the development of conditions such as chronic pain and psychiatric conditions. People who consume cannabis regularly may also have a lower quantity of cannabinoid receptors expressed on the surface of cells as the body adapts to repeated exposure of cannabinoids over time.